{"id":185243,"date":"2019-01-22T15:31:36","date_gmt":"2019-01-22T14:31:36","guid":{"rendered":"http:\/\/biomes.world\/interesting-facts\/der-darm\/chronic-intestinal-diseases\/crohns-disease\/morbus-chron-ursache\/"},"modified":"2022-06-27T11:59:14","modified_gmt":"2022-06-27T09:59:14","slug":"crohns-disease-causes","status":"publish","type":"post","link":"https:\/\/biomes.world\/en\/interesting-facts\/intestine\/chronic-disease\/crohns-disease\/crohns-disease-causes\/","title":{"rendered":"Crohn’s disease: possible causes of chronic illness"},"content":{"rendered":"\n

Scientists have been intensively researching Crohn’s disease and its causes for years. Nevertheless, the disease still poses a number of mysteries. It seems that several factors play a role in its onset.<\/p>\n\n\n\n

Basically, the barrier function of the intestinal mucosa is disturbed in Crohn’s disease patients. This allows bacteria to penetrate the intestinal mucosa that have no business being there. As a result, the immune system jumps into action and activates inflammatory cells. This reaction is very strong in Crohn’s disease patients and leads to chronic inflammation, which in severe cases can extend to the entire digestive system. The symptoms range from painful diarrhoea to inflammation of the oral mucosa.<\/p>\n\n\n\n

What factors can increase the risk of developing Crohn’s disease? And can an outbreak of the disease be prevented?<\/strong><\/em><\/p>\n\n\n\n

Is Crohn’s disease hereditary?<\/h2>\n\n\n\n

Scientists have already identified over 70 genes that may play a role<\/strong> in the development of Crohn’s disease. Changes in certain genes can increase the risk of Crohn’s disease. However, gene mutations are usually not solely responsible<\/strong> for the onset of the disease. Even those who have a genetically increased probability of developing Crohn’s disease often remain healthy. The connections that lead to the outbreak of the intestinal disease seem to be extremely complex and are influenced by external influences as well as the microbial conditions in the intestine, among other things.<\/p>\n\n\n\n

Environmental factors increase the risk of disease<\/h3>\n\n\n\n

Numerous studies have already tried to find out the connection between various environmental factors and Crohn’s disease. Some conditions seem to influence the risk of developing the disease:<\/strong><\/p>\n\n\n

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Country<\/div>

the country you live in<\/p>\n<\/div><\/div><\/div>

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Region<\/div>

whether you live in a rural region or in a city<\/p>\n<\/div><\/div><\/div>

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Environmental conditions<\/div>

the hygienic conditions prevailing there<\/p>\n<\/div><\/div><\/div> <\/div>\n<\/div>\n\n\n\n

Lifestyle influences the course of the disease<\/h3>\n\n\n\n

However, not only the place where one lives has an influence on the disease, but also the basic way of life. The following factors have a negative effect on the course of the disease<\/strong>:<\/p>\n\n\n\n